Crystal nephropathy and valacyclovir
WebThe cause was deduced to be oral valacyclovir, which was being used to treat herpes labialis, and ultimately caused crystal-induced nephrotoxicity. Due to the rapid … WebJun 25, 2024 · A 66-year-old women with no history of renal disease was admitted due to a coma and acute kidney injury with a serum creatinine level of 7.44 mg/dL which were ascribed to valacyclovir neurotoxicity and nephrotoxicity, respectively. She had received valacyclovir at a standard dosage for the treatment …
Crystal nephropathy and valacyclovir
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WebSep 1, 2008 · Acyclovir is associated with renal toxicity secondary to crystal-induced nephropathy, which is most commonly associated with intravenous bolus doses of … WebAug 31, 2010 · Acute kidney injury is an unfortunate complication of acyclovir therapy secondary to crystal-induced nephropathy. It is characterized by a decrease in renal function that develops within 24-48 ...
WebMar 28, 2024 · Valacyclovir is the valyl ester of the antiviral drug acyclovir [ 1 ]. Acting as an oral prodrug, valacyclovir is converted in vivo to acyclovir. Acyclovir, a nucleoside … WebIntratubular precipitation of these crystals can lead to acute renal insufficiency. Many patients who require treatment with these medications have additional risk factors, such …
WebOct 10, 2024 · Calcium oxalate is the most common type of crystal nephropathy on renal biopsy (Helen Liapis,unpublished results). The extent of oxalate crystals varies from a few foci to massive amounts. Acute presentation shows colorless crystals in tubules and/or the interstitium associated with varying degrees of tubular injury, usually ATI without ... WebSep 15, 2008 · Drugs associated with chronic interstitial nephropathy 11. , 20 – 23. Acetaminophen, aspirin, NSAIDs. History of chronic pain, age older than 60 years, female sex, cumulative consumption of ...
WebNov 15, 2011 · Acute interstitial nephritis, crystal nephropathy: Aminoglycosides: Tubular cell toxicity: Amphotericin B: Tubular cell toxicity: Chinese herbal preparations containing …
WebNov 15, 2011 · Acute interstitial nephritis, crystal nephropathy: Aminoglycosides: Tubular cell toxicity: Amphotericin B: ... Valacyclovir (Valtrex) 100%: Every 12 to 24 hours: 500 mg every 24 hours: sada systems careersWebMar 6, 2008 · Background: Several medications that are insoluble in human urine are known to precipitate within the renal tubules.Intratubular precipitation of either exogenously … sada thermal shirtsWebinduced nephropathy. The patient refused to undergo re-nal biopsy and was initiated on aggressive IV fluids. The patient’s renal function began to improve toward baseline over the following week. Discussion Valacyclovir is a widely used antiviral agent in herpetic in-fections and is approved as two single-dose therapy (2 g sada thioub transfermarktWebThe ability to cause crystal-induced nephropathy is well characterized in the literature as a mechanism for valacyclovir- and/or acyclovir-induced nephrotoxicity. Acyclovir is … iseal ffxiWebFeb 20, 2024 · Research in the crystal nephropathy field was once largely driven by the procedural approach of kidney-stone removal or by the morphological and descriptive … iseal consultationWebthrombocytopenia.Nephrotoxicity, including crystal nephropathy, is also a potential side effect of acyclovir but is more associated with intravenous administration and rare by oral route.Unfortunately side effects for valacyclovir are not commonly documented sada ms officeWebApr 8, 2024 · These results suggested that MSU crystal may induce kidney residential cell apoptosis in mice with hyperuricemic nephropathy, and RHF treatment at the medium and high doses could significantly inhibit the apoptosis, possibly by suppression of the p53-associated intrinsic apoptosis pathway. Download : Download high-res image (933KB) sada thioub pes