Tsc1f/f
WebBoth TSC1f/f LysM-Cre+ and LysM-Cre- mice were aerogenously infected with M. tuberculosis H37Rv with 200-300 bacilli per lung. Bacterial burdens were measured by … Web该TSC1 Polyclonal Antibody. This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.
Tsc1f/f
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WebWe allowed Tsc1f/f; Rosa26-CreERT2 glioma cells to form spheres in culture and then added 4-hydroxytamoxifen (4-OHT) to delete the Tsc1 gene. First, we confirmed that 4-OHT efficiently induced Tsc1 deletion in these sphere cells, as evidenced by the disappearance of TSC1 protein from lysates of sphere cells that had been cultured with 4-OHT ( Fig. 2 A ). WebNCBI's Gene Expression Omnibus (GEO) is a public archive and resource for gene expression data.
WebOverall design: p62F/F and Tsc1 F/F mice (Mori et al., 2009; Muller et al., 2013) were backcrossed to C57BL/6 mice for at least 7 generations, and then bred with Alb-Cre transgenic mice (also on C57BL/6 background) to generate p62F/F; Alb-Cre (p62Δhep) and Tsc1F/F; Alb-Cre (Tsc1Δhep)mice, respectively. p62Δhep mice were crossed to Tsc1Δhep ... Web(E and F) Change in body mass (E) and food consumption (F) in Tsc1f/fCD11cCre mice during chase with the gut microbiota of Tsc1f/f mice (n = 4–5; analyzed by two-way ANOVA with Sidak’s multiple comparisons test in E and t test in F), ∗p<0.05.
WebOct 2, 2024 · Abstract. Renal angiomyolipoma (AML) and cysts are seen in 70-80% of patients with the human tumor suppressor gene syndrome tuberous sclerosis complex … WebA reduction in mosaic regularity was observed for Lhx2-Cre:Tsc1f/f mice. The data represent the mean±s.e.m. of three mice from each genotype. (F) Quantification of RGC number in the tangential plane of control and Lhx2-Cre:Tsc1f/f mice. A decrease in the number of Brn3+ cells was observed in Lhx2-Cre:Tsc1f/f mice.
WebApr 27, 2024 · Vascular tumour cells were isolated from the cutaneous tumours in tamoxifen-induced Tsc1f/f; Scl-Cre mouse, and then transduced with hRasV12-GFP and …
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